How to Reconstitute Tirzepatide: Step-by-Step UK Guide

Reference guide. Next Day Pharma supplies pre-filled, ready-to-use injection pens — there is nothing to mix, and no vials, powder or bacteriostatic water are involved. This article is published as general reference information only.

Tirzepatide is supplied as a lyophilised powder that must be reconstituted with bacteriostatic water before use. This UK guide walks you through the exact process for 5mg, 10mg and 15mg vials and shows you the syringe units for the most common weekly doses.

What you need

  • 1 vial of lyophilised tirzepatide (5mg, 10mg or 15mg)
  • 1 vial of bacteriostatic water — see our BAC water product
  • 1 reconstitution syringe (3ml is ideal)
  • 1 insulin syringe (U-100, 0.5ml) for dosing
  • 2 alcohol swabs

The standard tirzepatide mix

The cleanest approach is to add 2 ml of bacteriostatic water to a 10 mg vial. That gives you a 5 mg/ml solution — which means 0.5 ml (50 units on a U-100 insulin syringe) equals a 2.5 mg dose. Halve the units to halve the dose.

Step-by-step reconstitution

  1. Bring both vials to room temperature.
  2. Wipe both rubber stoppers with an alcohol swab.
  3. Using a 3ml reconstitution syringe, draw 2 ml of bacteriostatic water.
  4. Insert the needle at an angle into the tirzepatide vial and let the water trickle slowly down the inside of the glass.
  5. Remove the needle, then gently swirl the vial in a circle on a flat surface until the powder is fully dissolved (usually within 30 seconds).
  6. Label the vial with the date — refrigerate immediately at 2–8°C.

Tirzepatide dose chart (10 mg vial in 2 ml BAC water)

Weekly doseVolumeInsulin syringe units
2.5 mg0.50 ml50 units
5.0 mg1.00 ml100 units (1 full syringe)
7.5 mg1.50 ml2 × 75 units
10.0 mg2.00 ml2 × 100 units

For other vial strengths, use our peptide dose calculator — it handles every common combination in seconds.

Titration schedule

The standard tirzepatide titration starts at 2.5 mg/week and escalates every 4 weeks. The full schedule is laid out in our dosage guide.

Frequently asked questions

How much bacteriostatic water do I add to a 10mg tirzepatide vial?

The cleanest ratio is 2 ml. That gives a 5 mg/ml solution where 50 units on a U-100 insulin syringe equals 2.5 mg.

Can I use sterile water instead?

You can, but the reconstituted vial only lasts about 24 hours. Bacteriostatic water extends that to 28 days refrigerated.

How long does reconstituted tirzepatide last?

Refrigerated at 2–8°C, 28 days. Discard after that or if the solution becomes cloudy.

Where can I buy tirzepatide in the UK?

Our tirzepatide product page has full purity certificates and next-day Royal Mail delivery.

This guide is provided for informational purposes by Next Day Pharma. All peptides supplied are FOR RECONSTITUTION. Always consult a qualified healthcare professional before use.